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The Future of Dermocosmetic Treatments

News 4 min read

Dermatological skin conditions affect an immense amount of people. They can vary greatly in symptoms and severity, but they all cause distress, and causing a series of impacts on the quality of life.

Most common skin conditions

Acne, rosacea, dermatitis, and hyperpigmentation are among the most common skin conditions, and they can affect the patient alone, simultaneously, or even as a consequence of each other.

  • Acne is an inflammatory skin condition that manifests in comedones, papules, pustules, and sometimes cysts and nodules. Acne lesions can cause scarring on the skin, leading to psychosocial impacts such as loss of self-confidence, anxiety, or commuting avoidance.
  • Rosacea is also an inflammatory condition that, similar to acne, also presents papules and pustules, but its main characteristics are intermittent skin redness, telangiectasias (small blood vessels on the skin), hyperplasia and hypertrophy of the sebaceous glands, and vasodilation.
  • Seborrheic dermatitis is another skin condition that can affect the skin of the face, causing erythema and scaling with associated pruritus.
  • Lastly, hyperpigmentation is a common skin condition characterized by an overproduction of melanin due to different stimuli that can be endogenous (hormone production, genetic predisposition) or exogenous (UV exposure, skin lesions, cosmetics, and medicines composition).

A common thread among these conditions is inflammation and sensitization, caused by the problem itself or as a consequence of their treatments, which sometimes use acidic or aggressive medicines to stimulate the renovation of the skin layers.

The role of Dermocosmetic treatments

Considering the many possible causes and the chronic aspects of different skin diseases, the focus of treatments is to control existing symptoms and limit the duration of the condition, avoiding permanent scarring as much as possible, along with other possible complications.

To choose the best strategy for treatment, individual patient factors must be taken into consideration, such as medical condition, disease state, the severity of the lesions, patient history, and the preferred type of treatment (oral or topical).

The selection of the active pharmaceutical ingredient (API) and its dosage should be based on the severity of each case. Most of these ingredients can be formulated in several forms. Their adequate combination with a suitable cream base can help decrease possible side effects, increase patient adherence to treatment, and improve the general aspect of the skin.

Cleoderm™ – Skin rebalancing cream

Cleoderm™ is a specially formulated topical cream for personalized dermatological treatments, developed with a unique blend of ingredients that are not only gentle on the skin but also serve as an ideal vehicle for compounded preparations, tailored for facial application.

This advanced formula has been designed to reduce sebum production, combat lipid peroxidation, and neutralize reactive oxygen species.

Key Highlights of Cleoderm™:

  • Specially formulated for personalized dermatological treatments.
  • Gentle on the skin, making it an ideal vehicle for facial applications.
  • Reduces sebum production, lipid peroxidation, and reactive oxygen species.
  • Inhibits Cutibacterium acnes proliferation and controls inflammation.
  • Ideal for addressing inflammatory skin conditions and situations where inflammation could worsen severity.

The ingredient profile of Cleoderm™ was carefully chosen to be gentle on the skin, promoting extra benefits to control skin inflammation. It contains:

  • Cleome gynandra, a plant with potent anti-inflammatory and antioxidant properties that acts to reduce the sebum production and the skin inflammation associated with acne;
  • Palmitoyl tripeptide-8, a soothing and anti-inflammatory lipopeptide that helps to reduce sensitiveness on the skin;
  • Bisabolol, a potent antioxidant, anti-inflammatory, and antibacterial agent that also improves the absorption of certain medicines;
  • Hyaluronic acid, a great moisturizer, and regenerator of the skin;
  • A blend of functional oils that act synergistically, providing multiple benefits such as anti-inflammatory, antimicrobial, antioxidant, calming, and moisturizer.

Cleoderm™ is dermatologically tested and non-comedogenic, and it is also free from allergens and irritant substances such as dyes, parabens, mineral oil, sodium lauryl sulfate, propylene glycol, and petrolatum.

Compounding with Cleoderm™

Cleoderm™ is an easy-to-compound-with vehicle, compatible with a wide range of active pharmaceutical and dermaceutical ingredients and different associations.

For a complete list of ingredients and formulations compounded with Cleoderm™, you can consult our latest updated Formulary and Compatibility Table on the product page.

Cleoderm™ is part of the Fagron Advanced Derma, a line of pharmaceutical dermal bases that are formulated according to the latest scientific knowledge in the field of dermatology. The vehicles are uniquely formulated to contain only ingredients for maximum safety and skin tolerance. The formulation of each base is based on specific skin types, and their gentleness and shin feel improve patient experience and compliance with therapy.