Cleoderm™ skin rebalancing cream is a functional vehicle with selected ingredients that makes it the ideal choice for compounding topical treatments for inflammatory skin conditions.

Dermatological skin conditions

Dermatological skin conditions are a large number of clinical manifestations that can affect between 30% and 70% of the population worldwide, and they can vary greatly in symptoms and severity. In the United States, they can affect one in every three Americans, and in 2013, skin diseases were responsible for $ 75 billion in costs to the healthcare system. In Europe, more than 40% of the population has already reported some kind of skin condition. Some of these conditions can present more or less impact on the quality of life of different individuals, and their knowledge is of high importance to determine the diagnosis, as well as the adequate treatment, both professional and home care. Acne, rosacea, dermatitis, and hyperpigmentation are among the most common ones, and they can affect the patient simultaneously, or as a consequence of each other.

Concept Brochures

Hyperpigmentation Brochure

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Cleoderm™ is a topical cream designed to be used as a vehicle for the compounding of personalized dermatological treatments. Its ingredient profile was specifically designed to be gentle on the skin to allow for its use as a vehicle for compounded preparations that may be applied to the face.

Cleoderm™ has a positive role in decreasing sebum production, lipid peroxidation, and reactive oxygen species, as well as inhibition of Cutibacterium acnes proliferation, and control of inflammation. The ingredient profile of Cleoderm™ makes it a good choice as a vehicle for topical use for inflammatory skin conditions, or conditions in which inflammation can worsen its severity.

Complementary Documents

Key facts and figures

reduction in sebum production
reduction in reactive oxygen species production
decrease in neutrophil migration

Cleoderm™ ingredients

Cleoderm™ is a functional vehicle with selected ingredients that makes it the ideal choice for compounding topical treatments for affected and sensitive skin. Its main constituents are Cleome gynandra L. leaf extract, palmitoyl tripeptide-8, bisabolol, hyaluronic acid, and functional oils (avocado, jojoba, dog rose, coconut, English lavender, tea tree, rosemary, shea tree, and vitamin E acetate). This unique combination of ingredients provides Cleoderm™ with great anti-inflammatory and humectant properties, as well as sebum production control.


• Highly spreadable
• Light skin feel
• Readily absorbed
• Non-comedogenic
• Dermatologically tested