Psoriasis is a common chronic and recurrent inflammatory skin disease characterized by the hyperproliferation of epidermal skin cells. Affected cells have an extremely high turnover rate, causing them to build up on the surface of the skin and form scaly plaques. Psoriasis can have a profound impact on a patient’s quality of life, affecting physical, psychological, social, sexual, and occupational activities.
As with many chronic skin diseases, life-long treatment is required. It is important for patients to experience maximum comfort during treatment to aid compliance and improve their quality of life. The availability of topical preparations that have a pleasant skin feel and produce minimal tackiness and greasiness is of crucial importance to this patient
Individual patient disease management is essential in the therapy of psoriasis and focuses on slowing down excessive cell reproduction to reduce skin inflammation and providing hydration with active pharmaceutical ingredients (APIs) and dermaceutical ingredients (DCIs).
The use of dermal vehicles
Dermal vehicles are base creams developed for basic skincare, individualized dermatological care, and compounded pharmaceutical treatment. Every skin is unique, and each skin type will react differently to various base creams. For the right skincare and dermal solution, it is important to know the patient’s specific skin needs.
Fagron Advanced Derma products are pharmaceutical dermal bases that are formulated according to the latest scientific knowledge in the field of dermatology. The vehicles are uniquely formulated to contain only ingredients for maximum safety and skin tolerance. The formulation of each base is based on specific skin types, and their gentleness and shin feel improve patient experience and compliance with therapy.
With Fagron Advanced Derma, patients are guaranteed a total solution for both customized prescription compounding and basic skincare.
Fagron Advanced Derma
Fagron offers products that are not greasy or uncomfortable. With Fagron Advanced Derma, patients are guaranteed a total solution for both customized prescription compounding and basic skin care based on:
• Vehicle design according to the latest scientific insights into the safety and tolerance of topically applied ingredients
• Different bases for different skin types
• Suitability for vulnerable, sensitive skin
• Optimal compatibility with a broad range of APIs and DCIs
• A formulary containing different formulations for easy prescribing and compounding by indication
Fagron Advanced Derma ensures continuous care for the skin during the exacerbation and maintenance phases and guarantees maximum patient comfort for optimal compliance and results.
All vehicles are developed and scientifically tested to help pharmacists compound stable preparations with a broad range of active pharmaceutical (APIs) and dermaceutical ingredients (DCIs).
The Fagron Advanced Derma vehicles are free from parabens, boric acid, Ethoxylates and 1,4-dioxane, Formaldehyde donors, mineral oils, Propylene Glycol, Benzyl alcohol, and benzyl benzoate, peanut oil, fragrances and dyes, triclosan, lanolin (wool fat), Phthalates, Para-aminobenzoic acid, Sodium Lauryl Sulfate (SLS), Nitrosamines.
A wide range of compatibility and stability studies have been conducted to support prescribers and pharmacists in vehicle selection as part of the treatment consideration.
Fagron Advanced Derma and Psoriasis
Finding or evaluating the compatibility of APIs and DCIs with topical vehicles can be challenging and time-consuming for the pharmacist, as well as incur in costs for the stability studies needed. Having then ready-to-use vehicles with determined compatibility with APIs and DCIs is a valuable tool for the compounding pharmacist.
Fagron Advanced Derma vehicles Occluvan™, Emolivan™, and Versatile™ Rich are then perfect choices for the compounding of treatments for psoriatic patients. They have proven compatibility with the most prescribed substances for psoriasis treatment (e.g., anthralin, coal tar, clobetasol, hydrocortisone, tacrolimus, aloe vera, etc.) together with maximum patient comfort and hydration without skin irritation. That’s what makes Fagron Advanced Derma so attractive for the pharmacist that needs to compound treatments for psoriasis.