The importance of excipients for a dosage form
Excipients are essential for compounding pharmaceutical dosage forms. For a long time, it was believed that excipients were pharmacologically inert substances used solely to optimize the handling of powders, to protect the API or to facilitate its transport. Currently, in addition to their traditional functions, the excipients need to play the role of an adjuvant, assisting the API to promote its activity through influence on the release from the pharmaceutical dosage form. Therefore, it is considered an essential ingredient for the formulation’s good performance, ensuring correct bioavailability, solubility, stability, dose accuracy, and improvement of organoleptic characteristics. In addition, it is yet favoring greater adherence to treatment.