This study aimed to investigate the proliferative potential of Trichotech (1% and 2%) on cultured human fibroblasts and its ability to modulate the gene expression of FGF-7 and FGF-10. Trichotech was found to increase the collagen content and the expression of FGF-7 and FGF-10 in treated fibroblasts.

The objective of this study was to evaluate the permeability of oxandrolone in human skin. 25.9% of the applied dose was able to permeate through a non-damaged skin, suggesting transdermal oxandrolone could be a viable alternative for traditional oral form.

The objective of this study was to evaluate the feasibility of 10 commonly used active pharmaceutical ingredients (APIs) compounded in SyrSpend® SF PH4 liquid. The expiration date of the final products (API + vehicle) was at least 90 days for all suspensions with regard to both the controlled temperatures.

The objective of this study was to evaluate the stability of 10 commonly used active pharmaceutical ingredients. The beyond-use dates of the preparations were found to be at least 90 days for all suspensions, both for controlled refrigerated temperature and room temperature.

The objective of this study was to evaluate the compatibility of 10 commonly used APIs compounded in SyrSpend SF PH4. Given the percentage of recovery of the APIs the expiration date of all products (API+vehicle) was found to be at least 90 days, for both controlled refrigerated and RT.

The aim of this study was to evaluate the physicochemical stability of 5 mg/mL oxybutynin oral suspension in Syrspend. These results indicate that microbiological stability and physical stability are acceptable but the concentration does not allow to go beyond 8 days.

The objective was to evaluate the microbiological and physicochemical compatibility of commonly used proton pump inhibitors (PPIs) esomeprazole, lansoprazole, omeprazole and pantoprazole compounded using SyrSpend SF Alka. Beyond-use dates of maximum 60 days for omeprazole (5 mg/mL), pantoprazole (3 mg/mL) and esomeprazole (3 mg/mL) were established.

The objective of this study was to evaluate the compatibility of 10 APIs in SyrSpend SF PH4. The beyond-use date was 90 days for most suspensions both refrigerated and RT. Exceptions: Minocycline hydrochloride at both storage temperatures (60 days), levodopa/carbidopa at RT (30 days), and lorazepam at RT (60 days).

The objective was to evaluate five transdermal vehicles for the compounding of ondansetron, dexamethasone, and aprepitant. Diffusion experiments showed that the release and permeation process were greater for ondansetron than for dexamethasone and aprepitant. When ondansetron and dexamethasone were compounded in combination in Pentravan® Plus, a permeation decrease was observed.

In this study, the in vitro permeation of an antibiotic, enrofloxacin, administered percutaneously to the shed skin of Python molurus bivittatus was analyzed. Results confirmed that enrofloxacin can be absorbed through the shed skin of snakes and investigated the percutaneous route as a new option for administering drugs when treating snakes.