In this paper, we describe the compatibility and disintegration times of 5-hydroxytryptophan (5-HTP) 50 mg, bromopride 5 mg, coenzyme Q10 20 mg, melatonin 3 mg, resveratrol 5 mg, tadalafil 10 mg, vitamin B12 1 mg, or vitamin D3 2000 UI in Orodispersible films (ODFs). The study showed that OrPhylloTM vehicle is suitable for compounding ODFs with APIs from different pharmacological classes, with good compatibility and fast disintegration.

The goal of the study was to present a possible option for the implementation of 3D-printed tablets into the digital Closed Loop Medication Management system; the required tablet formulation and development of the manufacturing process, as well as the pharmaceutical validation, were conducted. As a result, the developed method is suitable for the implementation of Closed-Loop Medication Management systems in hospital pharmacies and could, therefore, contribute to medication safety.

The present study evaluated the stability of amoxicillin trihydrate (50 mg/mL), clozapine (25 mg/mL), indomethacin (5.0 mg/mL), levodopa/carbidopa (10.0/2.5 mg/mL), levothyroxine sodium (T4, 25 µg/mL), lomustine (4.0 and 10.0 mg/mL), methyldopa (25 mg/mL) and procarbazine (10.0 mg/mL) in SyrSpend® SF PH4. The study demonstrated promising stability for the compounded suspensions, as all APIs exhibited stability throughout the study duration and met content uniformity criteria.

This study aimed to assess the physical–chemical, and microbiological stability and investigate the color change of compounded minoxidil formulations in TrichoSolTM or TrichoFoamTM. HPLC analyses and antimicrobial effectiveness testing were conducted in concentrations from 1.0% to 7.0% of minoxidil. The color change was noticeable, but no other quality attribute was affected. No precipitation was observed, and the pH was relatively stable.

This study investigated whether Miodesin (10 µg/mL = IC80; 200 µg/mL = IC50) could exert anti-inflammatory and anti-proliferative effects against Lipopolysaccharides stimulation in endometrial and Candida albicans vaginal cell lines. The study concludes that Miodesin presents beneficial effects in the context of endometriosis, positively affecting the inflammatory and proliferative response.

The aim of this study was to validate the efficacy of a new ultraviolet C light disinfection system in different environmental conditions. The device was effective in the neutralization of airborne particles containing coronavirus genus samples, presenting >99.99% of inactivation rate in an aerosolization test.

The testing conducted for the DiluCap line of excipients showed that all products have suitable flow properties, hygroscopicity, biopharmaceutical performance, and stability; supporting the use of this line of excipients by the compounding pharmacies with proven functionality that saves time and guarantees efficacy and safety of hard-shell oral capsules formulations.

The purpose of this study was to investigate the homogeneity and resuspendability of SyrSpend SF suspensions. HPLC analysis was performed for 104 different formulations with 89 unique active pharmaceutical ingredients . All samples in SyrSpend SF were compliant with the specifications set by the British Pharmacopoeia.

In this bracketed study, benzoyl peroxide, cyproterone acetate, estriol, metronidazole, niacinamide, progesterone, retinoic acid, spironolactone, and tranexamic acid were evaluated for compatibility and stability in Cleoderm™. For most formulations, a beyond-use date (BUD) of 180 days was observed when stored at room temperature, except for retinoic acid (BUD 30 days).

A method to prepare 0.2% oral erlotinib cream, without resorting to a pure active pharmaceutical ingredient, was developed. The proposed formulation is stable for at least 42 days at room temperature in Nourivan cream with antioxidant properties.