Fagron

Case study: Josh has problems swallowing
Josh's case
The challenge
The Case
Josh (51 years old) is recovering from a Laryngeal cancer treatment. He’s doing well but he’s having problems swallowing solid food and medication. His wife is currently suffering a bad flue. Since Josh’s immune system is considered to be acquired after his cancer treatment his oncologist wants to prescribe Josh an oseltamivir treatment to prevent him from developing influenza as well.
The challenge
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The Challenge
Patient accessibility: Because Josh is having problems swallowing he needs a liquid dosage form, which is not available as a licensed product in the right dosage strength for Josh.
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The Challenge
Patient acceptance: Josh is experiencing retching when feeling an unpleasant bitter taste in his mouth. Oseltamivir has a bitter taste.
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The Challenge
Unpleasant side effects: Josh is suffering diarrhea and other gastrointestinal discomfort due to his cancer medication. Stomach distress and diarrhoea are seen with sorbitol containing suspending vehicles.
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The Challenge
Proven stability: The stability of oseltamivir in a fluid form needs special attention.
The solution
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The Solution
With the focus on patient, prescriber and pharmacist, Fagron offers unique solutions that add significant value in the individualized treatment of patients with specific needs. Also for Josh.
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The Solution
Patient accessibility: With SyrSpend® SF PH4 it is possible for a pharmacist to easily compound a 15 mg/ml oseltamivir suspension for Josh, based on oseltamivir capsules. SyrSpend® SF PH4 can be used with a broad variety of active pharmaceutical ingredients (APIs) so the pharmacist can keep SyrSpend® SF PH4 on stock for similar cases similar cases.
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The Solution
Patient acceptance: SyrSpend® SF PH4 is available in cherry flavour and unflavoured, both with taste-masking capacities to cover the bitter taste of oseltamivir. Flavouring concentrates from the SyrSpend® SF Flavouring Kit may be added to the neutral versions to customise to Josh’s individual preference.
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The Solution
Unpleasant side effects: Low osmolality of SyrSpend® SF PH4 minimizes the risk of stomach distress and diarrhoea seen with traditional sorbitol containing suspending vehicles. The suspension prepared with SyrSpend® SF PH4 is free from alcohol, parabens, sorbitol, sugars, gluten and colourants. SyrSpend® SF PH4 is also available as a preservative-free powder for reconstitution.
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The Solution
Proven stability: Stability tests have proven a 30 days stability of a suspension of SyrSpend® SF PH4 with oseltamivir*.
The cure
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The Cure
A simple process of mixing the oseltamivir capsule contents with SyrSpend® SF PH4 enables the pharmacist to prepare a stable suspension in just minutes for Josh.
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The Cure
Josh is doing really well. He did not get caught by the influenza virus, his energy level is improving and he’s eating more and more solid food again. Last week he and his wife booked a holiday out of their dreams to Hawaii and he’s looking forward to it. Josh is enjoying life. * Voudrie MA, Allen DB. Stability of oseltamivir phosphate in SyrSpend® SF, cherry syrup, and SyrSpend® SF (for reconstitution). Int J Pharm Compd. 2010;14(1):82-85.
Case study: John is experiencing problems applying the product
John's case
The challenge
The Case
A 30-year-old male patient, John, required a repeat prescription for minoxidil base 5%. He complained to his pharmacist, Mrs Johnson, about the dripping and greasiness of the previous preparation when applying the product on his scalp to treat his alopecia.
The challenge
The solution
The Challenge
The scalp is, like other hairy skin parts, a difficult-to-treat area.
The solution
The Cure
The Solution
By compounding with the unique Fagron trademark vehicles from Fagron Advanced Derma, pharmacists are able to deliver exclusive solutions that add significant value and offer tailor-made treatment to patients. Patient satisfaction, therapy compliance and patients’ quality of life are thus improved.
The cure
Cases overview
The Cure
Mrs Johnson compounded minoxidil base 5% in Espumil™. To enhance treatment, she proposed to John’s prescriber that tretinoin 0.01% be added. John was very happy with the skin feel and user friendliness afforded by Espumil™. He has already brought his repeat prescription.
Case study: Steve has an unpleasant dry skin feeling
Steve's case
The challenge
The Case
Steve required a repeat prescription of benzoyl peroxide 5% and clindamycin HCl 1% in a gel for his acne. He complained to his pharmacist, Mr Nguyen, about the amount of time needed to apply the two products and an unpleasant dry skin feeling after frequent use.
The challenge
The solution
The Challenge
Due to Steve’s dehydrated skin condition, a cream would be better for his skin type than a gel, and combining both APIs in a single formulation would be preferable.
The solution
The Cure
The Solution
By compounding with the unique Fagron trademark vehicles from Fagron Advanced Derma, pharmacists are able to deliver exclusive solutions that add significant value and offer tailor-made treatment to patients. Patient satisfaction, therapy compliance and patients’ quality of life are thus improved.
The cure
Cases overview
The Cure
Mr Nguyen compounded benzoyl peroxide 5% and clindamycin HCl 1% in Versatile™ and was able to deliver an elegant single cream solution to Steve.
Case study: Sabine experiences a dehydrated skin
Sabine's case
The challenge
The Case
Sabine, a 40-year-old female patient with hyperpigmentation, required a prescription for hydroquinone 4% cream from her pharmacist, Simon Smith. She had been using this prescription for a long time and told Simon that she had recently started to experience dehydrated skin, which was vulnerable to winter conditions. Sabine asked him for advice on the best skin care option.
The challenge
The solution
The Challenge
Hydroquinone is an API susceptible to oxidation. For Sabine’s dehydrated skin, a solution containing hydroquinone in a single formulation would be preferable.
The solution
The Cure
The Solution
By compounding with the unique Fagron trademark vehicles from Fagron Advanced Derma, pharmacists are able to deliver exclusive solutions that add significant value and offer tailor-made treatment to patients. Patient satisfaction, therapy compliance and patients’ quality of life are thus improved.
The cure
Cases overview
The Cure
Simon Smith compounded hydroquinone 4% in Nourivan™ Antiox and was able to deliver an elegant single treatment skin care solution to Sabine. She commented that applying just one product was much more convenient and that there had been a marked improvement in her skin condition. She also requested additional advice about a tailor-made, anti-ageing solution.
Case study: Eric has a type III acne in the facial area
Eric's case
The challenge
The Case
Eric, a 16-year-old male patient with type III acne manifesting especially in the facial area, approached dermatologist Dr Naftaniel. The inflammatory condition sometimes produced painful areas, particularly when the skin was dehydrated. But, more important, Eric was socially embarrassed.
The challenge
The solution
The Challenge
Having tried all kinds of OTC treatments, bought by his compassionate mum, Eric’s skin condition only worsened. That’s when they consulted Dr Naftaniel. Eric turned out to have a very sensitive oily skin.
The solution
The Cure
The Solution
With the focus on patient, prescriber and pharmacist, Fagron Advanced Derma offers unique solutions that add significant value to the tailor-made treatment of patients with specific needs, including the acne patient with clear visible facial symptoms.
The cure
Cases overview
The Cure
Dr Naftaniel prescribed clindamycin HCl 1%, nicotinamide (vit. B3) 3% and tocopherol (vit. E) 5% in Fitalite™. The teenager’s skin condition improved dramatically within a month and is now controlled with a prescription of nicotinamide (vit. B3) 3% in Fitalite™.
Josh's case
John's case
Steve's case
Sabine's case
Eric's case

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